Recent Publication
Haoyu Tang, a postdoctoral researcher contributing to the research efforts of the Chang Lab in the Department of Chemistry, has collaborated with the Makris Lab and other researchers to publish a new article in the Journal of the American Society.
The study shows that BesC activates O2 in a substrate-gated manner to generate a diferric-peroxo intermediate. Examination of the reactivity of the peroxo intermediate with a series of lysine derivatives demonstrates that BesC initiates this unique reaction trajectory via cleavage of the C4–H bond;
Check it out https://doi.org/10.1021/jacs.1c11109
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