Yi Xiao
she, her, hers
Professor, LORD Corporation Distinguished Scholar, University Faculty Scholar
Department of Chemistry
Dabney Hall 612
919-515-2355 yxiao34@ncsu.eduEducation
Ph.D. Analytical Chemistry Nanjing University, P.R. China 2000
M.S. Analytical Chemistry Northwest University, P.R. China 1997
B.S. Analytical Chemistry Northwest University, P.R. China 1994
Area(s) of Expertise
Dr. Xiao’s group works on applications of biosensors and biotechnologies at the interface of chemistry, biochemistry, and molecular biology. The main goal of her research is centered around the development of aptamer selection techniques and aptamer-based sensor platforms, and the use of such advancements to develop sensitive, specific, cost-effective assays and devices for detection of medically- and forensically-relevant small-molecule targets in real-world samples.
Publications
- Improving Aptamer Affinity and Determining Sequence-Activity Relationships via Motif-SELEX , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2025)
- Determining the Precision of High-Throughput Sequencing and Its Influence on Aptamer Selection , ANALYTICAL CHEMISTRY (2024)
- Developing Aptamer-Based Colorimetric Opioid Tests , JACS AU (2024)
- Examining the Relationship between Aptamer Complexity and Molecular Discrimination of a Low-Epitope Target , ACS CENTRAL SCIENCE (2024)
- Exploring the Landscape of Aptamers: From Cross-Reactive to Selective to Specific, High-Affinity Receptors for Cocaine , JACS AU (2024)
- Generation of High-Affinity Aptamers for Indazole Synthetic Cannabinoids , ANALYTICAL CHEMISTRY (2024)
- High-Affinity Aptamers for In Vitro and In Vivo Cocaine Sensing , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2024)
- Nuclease-assisted selection of slow-off rate aptamers , SCIENCE ADVANCES (2024)
- Rapid Nuclease-Assisted Selection of High-Affinity Small-Molecule Aptamers , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2024)
- Aptamer-Based Fentanyl Detection in Biological Fluids , ANALYTICAL CHEMISTRY (2023)