Research Description

NMR and MRI are cherished for their molecular specificity and contrast rich images, but suffer from very low sensitivity. We develop hyperpolarization chemistry using para- hydrogen to enhance NMR and MRI signals by up to 6 orders of magnitude. This enables new applications such as portable NMR and cost- efficient molecular imaging.

Publications

• Micron-Scale NV-NMR Spectroscopy with Signal Amplification by Reversible Exchange (2021)
• SABRE and PHIP pumped RASER and the route to chaos (2021)
• Application of 15N2-Diazirines as a Versatile Platform for Hyperpolarization of Biological Molecules by d-DNP (2020)
• Automated pneumatic shuttle for magnetic field cycling and parahydrogen hyperpolarized multidimensional NMR (2020)
• Micron-scale SABRE-enhanced NV-NMR Spectroscopy (2020)
• Parahydrogen‐Induced Hyperpolarization of Gases (2020)
• Parahydrogen‐Induced Radio Amplification by Stimulated Emission of Radiation (2020)
• Parahydrogen‐Induced Radio Amplification by Stimulated Emission of Radiation (2020)
• Parawasserstoff‐induzierte Hyperpolarisation von Gasen (2020)
• Rational ligand choice extends the SABRE substrate scope (2020)

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Education

Ph.D., Chemistry, University of California at Berkeley (2012)
M.Sc., Chemistry, University of Göttingen (2006)