Dave Muddiman
He, Him, His
Jacob and Betty Belin Distinguished Professor of Chemistry, AAAS Fellow
Cox Hall 608
919-513-0084 dcmuddim@ncsu.edu WebsiteEducation
Postdoctoral Fellow Department of Energy Pacific Northwest National Laboratory 1997
Ph.D. Chemistry University of Pittsburgh 1995
B.S. Chemistry Gannon University 1990
Area(s) of Expertise
The Muddiman Group focuses on the development of innovative mass spectrometry measurements to solve important biological problems. Research projects include developing an ambient ionization method called IR-MALDESI and its application to a diverse range of materials, including soft tissue, plants, textiles and bone. Moreover, the group is working on advanced separations to enable detailed characterization of complex biological samples.
Publications
- Comparison of Mid-Infrared and Ultraviolet Lasers Coupled to the MALDESI Source for the Detection of Secondary Metabolites and Structural Lipids in Arabidopsis thaliana , JOURNAL OF MASS SPECTROMETRY (2025)
- Distinguishing the Metabolic Effect of Fetal and Adult Fibrinogen on Human Fibroblast Cell Culture by IR-MALDESI Mass Spectrometry Imaging , JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2025)
- Feasibility of IR-MALDESI Mass Spectrometry Imaging of PFAS , JOURNAL OF MASS SPECTROMETRY (2025)
- Glycosaminoglycan Mass Spectrometry Imaging by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization , JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2025)
- Mitochondrial Preparation from Microglia for Glycan Analysis , JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2025)
- Part A: Implementing an Analyte Panel and Sampling Protocol for Quality Control in Mass Spectrometry Imaging , RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2025)
- Part B: SLICE-MSI-A Machine Learning Interface for System Suitability Testing of Mass Spectrometry Imaging Platforms , RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2025)
- Three-dimensional mass spectrometry imaging (3D MSI): incorporating top-hat IR-MALDESI and automatic z-axis correction , ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2025)
- Topographic imaging with automatic z-axis correction of Brassica oleracea var. viridis leaves by IR-MALDESI mass spectrometry imaging , ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2025)
- Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics , ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2025)