Yi Xiao
Associate Professor, LORD Corporation Distinguished Scholar, University Faculty Scholar
she, her, hers
Department of Chemistry
Dabney Hall 612
Education
Ph.D. Analytical Chemistry Nanjing University, P.R. China 2000
M.S. Analytical Chemistry Northwest University, P.R. China 1997
B.S. Analytical Chemistry Northwest University, P.R. China 1994
Area(s) of Expertise
Dr. Xiao’s group works on applications of biosensors and biotechnologies at the interface of chemistry, biochemistry, and molecular biology. The main goal of her research is centered around the development of aptamer selection techniques and aptamer-based sensor platforms, and the use of such advancements to develop sensitive, specific, cost-effective assays and devices for detection of medically- and forensically-relevant small-molecule targets in real-world samples.
Publications
- Developing Aptamer-Based Colorimetric Opioid Tests , JACS AU (2024)
- Exploring the Landscape of Aptamers: From Cross-Reactive to Selective to Specific, High-Affinity Receptors for Cocaine , JACS AU (2024)
- High-Affinity Aptamers for In Vitro and In Vivo Cocaine Sensing , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2024)
- Aptamer-Based Fentanyl Detection in Biological Fluids , ANALYTICAL CHEMISTRY (2023)
- Comparison of Aptamer Signaling Mechanisms Reveals Disparities in Sensor Response and Strategies to Eliminate False Signals , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)
- Suite of Aptamer-Based Sensors for the Detection of Fentanyl and Its Analogues , ACS SENSORS (2023)
- Using Exonucleases for Aptamer Characterization, Engineering, and Sensing , ACCOUNTS OF CHEMICAL RESEARCH (2023)
- DNA Aptamer-Cyanine Complexes as Generic Colorimetric Small-Molecule Sensors , ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)
- High-throughput quantitative binding analysis of DNA aptamers using exonucleases , NUCLEIC ACIDS RESEARCH (2022)
- Near-Infrared Dye-Aptamer Assay for Small Molecule Detection in Complex Specimens , ANALYTICAL CHEMISTRY (2022)