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Event Series:
Organic Chemistry Seminar Series
Organic Chemistry Seminar Series: Jeff Rudolf – University of Florida
January 29 | 3:45 pm - 4:45 pm
About the Seminar:
Title:
Exploring the bacterial terpenome
Abstract:
Terpenoids are the largest and most structurally diverse family of natural products and are a rich reservoir of pharmaceuticals, vitamins, flavors, fragrances, and biofuels. There are over 90,000 known terpenoids but less than 2% of these (≅1500) are of bacterial origin. Genomics, however, supports vast untapped biosynthetic potential for terpenoids in bacteria. Here, we summarize some of our recent work on genome mining for bacterial terpenoids and the enzymes that create these structurally complex small molecules.
About the Speaker:
Bio:
Education and Training
2003–2007: B.S. Biochemistry, Walla Walla University
2007–2013: Ph.D. (Chemistry), University of Utah (lab of C. Dale Poulter)
2013–2018: Postdoctoral Fellow, Scripps Research (lab of Ben Shen)
Research Interests:
The Rudolf Lab works on discovering novel natural products from bacteria, understanding how they are made by Nature, and how they can be utilized and engineered for human health.
We are a member of the Chemical Biology Division within the Department of Chemistry at the University of Florida. Research in the Rudolf Lab is very multidisciplinary; students receive training in microbiology, genetics, genomics, bioinformatics, metabolomics, chemistry, biosynthesis, and enzymology.