Thomas Theis
Associate Professor, Goodnight Distinguished Scholar in Molecular Characterization
Pronouns: (He, Him, His)
Partners Building III 363 D
Education
Ph.D. Chemistry University of California at Berkeley 2012
M.Sc. Chemistry University of Göttingen 2006
Area(s) of Expertise
NMR and MRI are cherished for their molecular specificity and contrast rich images, but suffer from very low sensitivity. We develop hyperpolarization chemistry using para- hydrogen to enhance NMR and MRI signals by up to 6 orders of magnitude. This enables new applications such as portable NMR and cost- efficient molecular imaging.
Publications
- 13C MRI of hyperpolarized pyruvate at 120 µT , Scientific Reports (2024)
- Carbon-13 Radiofrequency Amplification by Stimulated Emission of Radiation of the Hyperpolarized Ketone and Hemiketal Forms of Allyl [1-13C]Pyruvate , ACS SENSORS (2024)
- C-13 Radiofrequency Amplification by Stimulated Emission of Radiation Threshold Sensing of Chemical Reactions , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)
- Delivering Robust Proton-Only Sensing of Hyperpolarized [1,2-13C2]-Pyruvate Using Broad-Spectral-Range Nuclear Magnetic Resonance Pulse Sequences , ACS SENSORS (2023)
- Efficient SABRE-SHEATH Hyperpolarization of Potent Branched-Chain-Amino-Acid Metabolic Probe [1-C-13]ketoisocaproate , METABOLITES (2023)
- Exploring synchrony and chaos of parahydrogen-pumped two-compartment radio-frequency amplification by stimulated emission of radiation , PHYSICAL REVIEW A (2023)
- Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1-13C]pyruvate in vivo , ChemRxiv (2023)
- Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1-13C]pyruvate in vivo , JOURNAL OF MAGNETIC RESONANCE OPEN (2023)
- Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1-13C]pyruvate in vivo , SSRN (2023)
- Innentitelbild: Parahydrogen‐Induced Carbon‐13 Radiofrequency Amplification by Stimulated Emission of Radiation (Angew. Chem. 5/2023) , Angewandte Chemie (2023)