Leslie Sombers

Area(s) of Expertise

The development, characterization and application of electroanalytical techniques to study real-time neurochemical fluctuations in systems ranging from single cells in culture to the brain of an awake, behaving animal. The ability to directly monitor these chemical messengers provides insight into the kinetics with which information is conveyed between neurons in response to environmental stimuli, the mechanisms that regulate these signals, and the behavioral implications of this neurochemistry.

Publications

• Dioxythiophene/Nafion Polymer Composite Membranes for Tunable Size-Based Selectivity in the Voltammetric Detection of Small Neuropeptides , ACS SENSORS (2024)
• Electrochemical Quantification of Enkephalin Peptides Using Fast-Scan Cyclic Voltammetry , ANALYTICAL CHEMISTRY (2024)
• Maximizing Electrochemical Information: A Perspective on Background-Inclusive Fast Voltammetry , ANALYTICAL CHEMISTRY (2024)
• Optimized Fabrication of Carbon-Fiber Microbiosensors for Codetection of Glucose and Dopamine in Brain Tissue , ACS SENSORS (2024)
• A Student Perspective on the 18th Monitoring Molecules in Neuroscience Meeting in Lyon , ACS CHEMICAL NEUROSCIENCE (2023)
• Exploiting Microelectrode Geometry for Comprehensive Detection of Individual Exocytosis Events at Single Cells , ACS SENSORS (2023)
• Exploring Electrochemistry: A Hydrogen Peroxide Sensor Based on a Screen-Printed Carbon Electrode Modified with Prussian Blue , JOURNAL OF CHEMICAL EDUCATION (2023)
• Monitoring Molecules in Neuroscience , ACS CHEMICAL NEUROSCIENCE (2023)
• Simultaneous, Real-Time Detection of Glutamate and Dopamine in Rat Striatum Using Fast-Scan Cyclic Voltammetry , ACS SENSORS (2023)
• Untapped Potential: Real-Time Measurements of Opioid Exocytosis at Single Cells , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)