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Physical Chemistry Seminar Series: Boyd Goodson (Southern Illinois University)
April 5, 2022 | 4:00 pm - 5:00 pm
About the Speaker:
A.B., Princeton University
Ph.D., University of California, Berkeley
Postdoctoral Scholar, NSF Laboratory for Molecular Sciences at the California Institute of Technology
Current research interests of the Goodson Group: NMR and MRI enjoy wide applicability but suffer from poor detection sensitivity. For this reason, imaging and spectroscopy of low-concentration species—such as gases in lung spaces or metabolites in tissues—can be particularly challenging. To combat such problems, we are pursuing two “hyperpolarization” methods: (1) spin-exchange optical pumping (SEOP), a technique whereby high-power lasers are used to prepare hyperpolarized noble gases (primarily for enhanced biological imaging and spectroscopic applications); and (2) Signal Amplification by Reversible Exchange (“SABRE”), a chemical process where organometallic catalysts are used to transfer the high nuclear spin order of para-hydrogen to molecular agents for applications—including for ultimate use as metabolic MRI contrast agents to probe responses to treatment of various diseases.
About the Seminar:
‘Cutting-Edge’ Tools to Hyperpolarize NMR and MRI: From Lasers to SABRE